(Northern) January 25, 2024: 9th George J. Rosenbaum, M.D., Lecture in Primary Care and Psychiatry - Bidirectional brain-immune interactions in stress and depression
Bidirectional brain-immune interactions in stress and depression
Scott Russo, PhD
Leon Levy Director of the Brain-Body Research Center and Professor of Neuroscience and Psychiatry
Dalia Professor in Mood Disorders
Studies have shown that chronic stress, which precipitates depressive symptoms, can activate myeloid cells in the periphery that secret factors that gain access to the brain through damaged vessels to regulate reward processing. This lecture will discuss data implicating systemic immune factors in depression and related stress disorders will discuss data implicating systemic immune factors in depression and related stress disorders.
This program is intended for: Psychiatrists, Psychologists, Fellows, Residents, Interns and Nurses
Upon completion of the activity, participants will be able to:
1.Describe how stress affects the blood brain barrier.
2.Discuss changes in immune cells and secreted factors that occur in depressed patients.
3.Identify direct mechanisms by which the brain can affect immune compartments in peripheral organs
Scott Russo, PhD Leon Levy Director of the Brain-Body Research Center and Professor of Neuroscience and Psychiatry
Dr. Russo has no disclosures to report.
Dr. Russo is Professor of Neuroscience and Leon Levy Director of the Brain Body Research Center and Center for Affective Neuroscience at the Icahn School of Medicine at Mount Sinai. He obtained his Ph.D. in Psychology from the City University of New York in 2003. He then completed his postdoctoral work in Psychiatry and Psychology at the University of Texas Southwestern Medical Center before joining the faculty at the Icahn School of Medicine in 2008. Dr. Russo is known for his contributions to understanding the neural and immunological basis of neuropsychiatric disorders. His translational studies have identified novel disease mechanisms in depressed humans that play causal roles in the expression of depression-like behaviors in rodent models. He has also identified novel circuitry in the brain that control aberrant social behaviors leading to new perspectives about social dysfunction in neuropsychiatric illness. His work has been highly cited in the field and featured in the popular press. Thomson-Reuters listed him as a “highly cited researcher”.He has received numerous honors and awards in recognition of his work, including being named a Kavli National Academy of Science Frontiers Fellow in2009, received the Johnson and Johnson/IMHRO Rising Star Translational Research Award in 2011 and elected fellow of the American College of Neuropsychopharmacology in 2016
- 1.00 AMA PRA Category 1 Credit™
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of McLean Hospital and Massachusetts General Hospital. McLean Hospital is accredited by the ACCME to provide continuing medical education for physicians.
McLean Hospital designates this Live activity for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
- 1.00 Nursing Contact Hours
Massachusetts General Laws, Chapter 13, sections 13, 14, 14A, 15 and 15D and Chapter 112, sections 74 through 81C authorize the Board of Registration in Nursing to regulate nursing practice and education.
This program meets the requirements of the Massachusetts Board of Registration in Nursing (244 CMR 5.00) for 1.00 contact hours of nursing continuing education credit. Advance practice nurses, please note: Educational activities which meet the requirements of the ACCME (such as this activity) count towards 50% of the nursing requirement for ANCC accreditation.
- 1.00 Participation
This course allows other providers to claim a Participation Certificate upon successful completion of this course.
Participation Certificates will specify the title, location, type of activity, date of activity, and number of AMA PRA Category 1 Credit™ associated with the activity. Providers should check with their regulatory agencies to determine ways in which AMA PRA Category 1 Credit™ may or may not fulfill continuing education requirements. Providers should also consider saving copies of brochures, agenda, and other supporting documents.
- 1.00 Psychologists CE Credit
The Massachusetts General Hospital Department of Psychiatry is approved by the American Psychological Association to sponsor continuing education for psychologists. The Massachusetts General Hospital Department of Psychiatry maintains responsibility for this program and its content.
This offering meets the criteria for 1.00 Continuing Education (CE) credits per presentation for psychologists.
In support of improving patient care, MGH Institute of Health Professions is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
MGH Institute of Health Professions designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credits ™. Physicians should claim only credit commensurate with the extent of their participation in this activity.
1.00 Nursing Contact Hours
MGH Institute of Health Professions designates this activity for 1.00 contact hours for nurses.
1.00 Social Workers
As a Jointly Accredited Organization, MGH Institute of Health Professions is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. MGH Institute of Health Professions maintains responsibility for this course. Social workers completing this course receive 1.00 clock hours for continuing education credits.
1.00 IPCE Credit
This activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.