Center for Morphometric Analysis,

Departments of Psychiatry and Neurology,

Massachusetts General Hospital, Harvard Medical School

Dr. Nikos Makris is a neuroanatomist and imager whose work is principally in human and non-human primate quantitative neuroanatomy and the development of imaging methodologies that translate basic brain science into the clinical domains of psychiatry, neurology and neurosurgery. His principal accomplishments are in the fields of structural and functional brain imaging and imaging method development to solve problems in brain structure and function in studying aging and neuropsychiatric conditions such as neurodegeneration, drug addiction, psychosis, and stroke. His lab has been at the forefront of MRI brain morphometry and diffusion imaging of brain circuitries since the beginning of these fields of research. In 1997, he validated the diffusion tensor imaging (DTI) methodology and showed for the first time the association corticocortical fiber tracts in the human brain in vivo. His expertise in human neuroanatomy has been critical in the original validation of High-Angular Resolution Diffusion Imaging (HARDI) or Diffusion Spectrum Imaging (DSI) and of the automated methodologies for brain morphometric analysis, namely brain segmentation and cerebral cortical parcellation distributed by the FreeSurfer software. He has achieved significant discoveries in the field of neuroanatomy of the human brain and in neuroimaging and has a leadership role in teaching and mentoring.