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ForwardOctober 16, 2025: The 15th Peter Miller Musser Lecture in Depression - Depressive Disorders in Women: Interrogating Female-Specific Contributions and Translating to Therapeutic Strategies
Depressive Disorders in Women: Interrogating Female-Specific Contributions and Translating to Therapeutic Strategies
Description:
This talk provides an overview of the course of depressive disorders in women over the lifespan, focusing on the reproductive lifecycle, from menarche to menopause. The lecture will characterize female-specific contributions to depression risk, including hormonal and comorbid symptoms, during midlife and the menopause transition. Implications for clinical strategies and available treatment approaches will be discussed.
Target Audience
This program is intended for Psychiatrists, Psychologists, General and Family Practice Physicians, Psychiatric Nurses, Physician Assistants, Nurse Practitioners, and Social Workers.
Learning Objectives
Upon completion of the activity, participants will be able to:
- Understand the course of depressive disorders in women over the lifespan.
- Characterize female-specific contributors to depression risk in midlife.
- Identify clinical strategies for treatment approaches for depressive and sleep disorders across menopause.
SPEAKER(S)
Hadine Joffe, MD, MSC
Paula A. Johnson, Professor of Psychiatry in the Field of Women’s Health, Harvard Medical School
Executive Director, Mary Horrigan Connors Center for Women’s Health Research
Founder and Director, Women’s Hormones and Aging Research Program, Department of Psychiatry, Brigham and Women’s Hospital
Research Affiliate, Department of Supportive Oncology / Breast Cancer Program, Dana Farber Cancer Institute
Research Affiliate, Division of Sleep Medicine, Harvard Medical School
Hadine Joffe, MD, MSC
Hadine Joffe, MD, MSc, is a clinical reproductive neuroscientist and academic psychiatrist whose research has advanced understanding of depression and related neurocognitive symptoms in midlife women. Dr. Joffe’s research focuses on the mechanisms, course, and treatment of depression, insomnia, thermoregulatory symptoms, and fatigue in women navigating the menopause transition or undergoing breast cancer treatment. She has led NIH-funded studies for over 25 years, including as Principal Investigator on three R01S and a U54 Specialized Center of Research Excellence (SCORE) focused on sex differences in health and disease.
Her work integrates neural, hormonal, neurosteroid, stress, and autonomic pathways to better characterize the biological underpinnings of depression and associated symptoms in midlife women, and their downstream consequences on metabolism and anti-estrogen adherence.
At the Connors Center, she leads research initiatives addressing equity in drug development and the effects of stress and adversity on women’s health. She is a committed mentor, having supported the careers of over 100 investigators and clinicians. Her contributions have been recognized through numerous local and national awards, and she continues to shape the fields of women’s mental health and translational neuroscience through research, mentorship, and leadership.
Disclosures:
Available Credit
- 1.00 AMA PRA Category 1 Credit™
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of IHP and Massachusetts General Hospital. IHP is accredited by the ACCME to provide continuing medical education for physicians.
IHP designates this Enduring activity for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
- 1.00 Nursing Contact Hours
Massachusetts General Laws, Chapter 13, sections 13, 14, 14A, 15 and 15D and Chapter 112, sections 74 through 81C authorize the Board of Registration in Nursing to regulate nursing practice and education.
This program meets the requirements of the Massachusetts Board of Registration in Nursing (244 CMR 5.00) for 1.00 contact hours of nursing continuing education credit. Advance practice nurses, please note: Educational activities which meet the requirements of the ACCME (such as this activity) count towards 50% of the nursing requirement for ANCC accreditation.
- 1.00 Social Workers
As a Jointly Accredited Organization, the MGH Institute of Health Professions is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. MGH Institute of Health Professions maintains responsibility for this course. Social workers completing this course receive 1.00 clock hours for continuing education credits.
- 1.00 Participation
This course allows other providers to claim a Participation Certificate upon successful completion of this course.
Participation Certificates will specify the title, location, type of activity, date of activity, and number of AMA PRA Category 1 Credit™ associated with the activity. Providers should check with their regulatory agencies to determine ways in which AMA PRA Category 1 Credit™ may or may not fulfill continuing education requirements. Providers should also consider saving copies of brochures, agenda, and other supporting documents.
- 1.00 Psychologists CE Credit
Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs. MGH Institute of Health Professions designates this activity for 1.00 CE credit.
Accreditation
In support of improving patient care, MGH Institute of Health Professions is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
1.0 Physicians
MGH Institute of Health Professions designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits ™. Physicians should claim only credit commensurate with the extent of their participation in this activity.
1.0 Physician Associates/Assistants
AAPA Credit Designation Statement – Live
MGH Institute of Health Professions has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
AAPA Credit Designation Statement – Enduring Materials
MGH Institute of Health Professions has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. Approval is valid until {Expiration Date). PAs should only claim credit commensurate with the extent of their participation.
1.0 Nursing
MGH Institute of Health Professions designates this activity for 1.0 contact hours for nurses. The American Academy of Nurse Practitioners Certification Board (AANPCB) accepts credit from organizations accredited by the ACCME and ANCC.
1.0 Pharmacists
This activity provides 1.0 contact hours of continuing education credit.
NOTE FOR PHARMACISTS: Upon closing of the electronic evaluation, IHP will upload the pharmacy-related continuing education information to the CPE Monitor within 60 days. Per ACPE rules, IHP does not have access nor the ability to upload credits requested after the evaluation closes. It is the responsibility of the pharmacist or pharmacy technician to provide the correct information [NABP ePID and DOB (in MMDD format)] in order to receive credit for participating in a CE activity.
1.0 Psychologists:
Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs. MGH Institute of Health Professions designates this activity for 1.0 CE credit.
1.0 Social Workers
As a Jointly Accredited Organization, MGH Institute of Health Professions is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. MGH Institute of Health Professions maintains responsibility for this course. Social workers completing this course receive 1.0 clock hours for continuing education credits.
1.0 IPCE Credit
This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credit for learning and change.