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ForwardDecember 18, 2025: 14th Gary Jacobson, M.D., Susan B. Jacobson, Lecture on Promising Innovations in Psychiatry - Targeting Circuits to Personalize Care: Developing Precision Neuromodulation Therapies for Suicide (Northern)
Targeting Circuits to Personalize Care: Developing Precision Neuromodulation Therapies for Suicide
Description:
This lecture presents a biomarker-driven framework for precision neuromodulation, illustrated through the development of targeted interventions for suicidal thoughts and behaviors. It traces an empirical pathway from the identification of a suicide-specific response biomarker using combined ECT and MRI to hypothesis generation within an experimental medicine framework, culminating in a novel fMRI-guided accelerated TMS protocol demonstrating early evidence for target engagement and clinical efficacy.
Target Audience
This program is intended for Psychiatrists, Psychologists, General and Family Practice Physicians, Psychiatric Nurses, Physician Assistants, Nurse Practitioners, and Social Workers.
Learning Objectives
Upon completion of the activity, participants will be able to:
- Describe key neural circuits implicated in suicidality and their relevance to clinical assessment and treatment planning.
- Explain how advances in neuroimaging and neuromodulation inform personalized targeting strategies for suicide-focused interventions.
- Apply circuit-based principles to conceptualize individualized neuromodulation approaches for patients at elevated suicide risk.
SPEAKER(S)
Joan Camprodon, MD, MPH
Joan Camprodon, MD, MPH
Dr. Camprodon is the Chief of the Division of Neuropsychiatry and Interventional Psychiatry at Mass General Brigham and Associate Professor of Psychiatry and Neurology at Harvard Medical School.
Clinically, he is the founding director of the MGH Transcranial Magnetic Stimulation (TMS) clinical service, co-director of the MGH Psychiatric Neurosurgery Committee, and an attending physician in the departments of Psychiatry (Neuropsychiatry) and Neurology (Cognitive and Behavioral Neurology). He created and now co-directs the MGH/MGB clinical fellowship in Interventional Neuropsychiatry and Neuromodulation, the first of its kind in the country, and he is board-certified in Psychiatry and Behavioral Neurology & Neuropsychiatry
Scientifically, he directs the Laboratory for Circuit Neuroscience and Neuromodulation and serves as a founding member of the executive committee of the MGH Interdisciplinary Brain Center. Methodologically, his research uses multimodal combinations of neuromodulation (noninvasive, convulsive, and surgical), neuroimaging, neurophysiology, behavioral, and clinical assays to investigate brain circuits and plasticity. The scope of his research includes basic, translational, and clinical projects focused on human circuit neuroscience. Projects in his laboratory address (1) the anatomy, physiology, and behavioral computations of disease-relevant networks, (2) the investigation of pathophysiological mechanisms at the circuit level (with an emphasis on transdiagnostic processes and the role of plasticity), and (3) the translational and clinical development of tools to support clinical care and decision-making (e.g., biomarker discovery and treatment development). Critical efforts are geared towards applying the paradigms and methods of human systems/cognitive neuroscience to discover treatment targets and develop individualized precision circuit therapeutics, with an emphasis on device neuromodulation.
Disclosures: SAB: Flow Neurosciences, Grey Matters Neuroscience; Consultant: Neuroelectrics, Fisher Wallace
Available Credit
- 1.00 AMA PRA Category 1 Credit™
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of IHP and Massachusetts General Hospital. IHP is accredited by the ACCME to provide continuing medical education for physicians.
IHP designates this Enduring activity for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
- 1.00 Nursing Contact Hours
Massachusetts General Laws, Chapter 13, sections 13, 14, 14A, 15 and 15D and Chapter 112, sections 74 through 81C authorize the Board of Registration in Nursing to regulate nursing practice and education.
This program meets the requirements of the Massachusetts Board of Registration in Nursing (244 CMR 5.00) for 1.00 contact hours of nursing continuing education credit. Advance practice nurses, please note: Educational activities which meet the requirements of the ACCME (such as this activity) count towards 50% of the nursing requirement for ANCC accreditation.
- 1.00 Social Workers
As a Jointly Accredited Organization, the MGH Institute of Health Professions is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. MGH Institute of Health Professions maintains responsibility for this course. Social workers completing this course receive 1.00 clock hours for continuing education credits.
- 1.00 Participation
This course allows other providers to claim a Participation Certificate upon successful completion of this course.
Participation Certificates will specify the title, location, type of activity, date of activity, and number of AMA PRA Category 1 Credit™ associated with the activity. Providers should check with their regulatory agencies to determine ways in which AMA PRA Category 1 Credit™ may or may not fulfill continuing education requirements. Providers should also consider saving copies of brochures, agenda, and other supporting documents.
- 1.00 Psychologists CE Credit
Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs. MGH Institute of Health Professions designates this activity for 1.00 CE credit.
Accreditation
In support of improving patient care, MGH Institute of Health Professions is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
1.0 Physicians
MGH Institute of Health Professions designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits ™. Physicians should claim only credit commensurate with the extent of their participation in this activity.
1.0 Physician Associates/Assistants
AAPA Credit Designation Statement – Live
MGH Institute of Health Professions has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
AAPA Credit Designation Statement – Enduring Materials
MGH Institute of Health Professions has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. Approval is valid until {Expiration Date). PAs should only claim credit commensurate with the extent of their participation.
1.0 Nursing
MGH Institute of Health Professions designates this activity for 1.0 contact hours for nurses. The American Academy of Nurse Practitioners Certification Board (AANPCB) accepts credit from organizations accredited by the ACCME and ANCC.
1.0 Pharmacists
This activity provides 1.0 contact hours of continuing education credit.
NOTE FOR PHARMACISTS: Upon closing of the electronic evaluation, IHP will upload the pharmacy-related continuing education information to the CPE Monitor within 60 days. Per ACPE rules, IHP does not have access nor the ability to upload credits requested after the evaluation closes. It is the responsibility of the pharmacist or pharmacy technician to provide the correct information [NABP ePID and DOB (in MMDD format)] in order to receive credit for participating in a CE activity.
1.0 Psychologists:
Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs. MGH Institute of Health Professions designates this activity for 1.0 CE credit.
1.0 Social Workers
As a Jointly Accredited Organization, MGH Institute of Health Professions is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. MGH Institute of Health Professions maintains responsibility for this course. Social workers completing this course receive 1.0 clock hours for continuing education credits.
1.0 IPCE Credit
This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credit for learning and change.