Time

Content

Speaker

12:00pm-12:10pm

 Welcome Remarks

Jordan Smoller, MD, ScD,

Director, MGH Center for Precision Psychiatry; Professor of Psychiatry, Harvard Medical School; Director, Psychiatric and Neurodevelopmental Genetics Unit, MGH Center for Genomic Medicine

12:10pm-12:50pm

 Conference Keynote

Leanne Williams, PhD,

Professor of Psychiatry and Behavioral Sciences and Founding Director of the Stanford Center for Precision Mental Health

12:50pm–1:10pm

Moderated Discussion/Q&A:

Jordan Smoller, MD, ScD,

Director, MGH Center for Precision Psychiatry; Professor of Psychiatry, Harvard Medical School; Director, Psychiatric and Neurodevelopmental Genetics Unit, MGH Center for Genomic Medicine

 1:10pm–1:15pm

Brief Section Introduction

 1:15pm–2:00pm

Therapeutic Opportunities for Precision Psychiatry

 1:15pm–2:00pm

Panel Moderator:

Karmel Choi, PhD,

Clinical Psychologist and Assistant Professor at Harvard Medical School/Massachusetts General Hospital

Alex Goddard, PhD,

Director, McQuade Center for Strategic Research and Development, Otsuka Pharmaceutical Companies (U.S.)

Alan Anticevic, PhD,

Sr. Director, Neuroscience at Johnson & Johnson and Co-founder & President at Manifest Technologies

Marinka Zitnik, PhD,

Associate Professor of Biomedical Informatics, Harvard Medical School; Associate Faculty, Kempner Institute for the Study of Natural and Artificial Intelligence, Harvard University

 2:00pm–2:10pm

BREAK

 2:10pm–2:15pm

Brief Section Introduction

 2:15pm–3:35pm

Biomarkers and Neuroimaging

 2:15pm–2:40pm

Edward Boyden, PhD,

Professor, Departments of Brain and Cognitive Sciences, Media Arts and Sciences, and Biological Engineering and Y. Eva Tan Professor in Neurotechnology at the McGovern Institute and HHMI; Co-Director, Center for Neurobiological Engineering and Co-Director, K. Lisa Yang Center for Bionics at MIT

2:40pm–3:05pm

M. Brandon Westover, MD, PhD,

Associate Professor of Neurology at Massachusetts General Hospital and Harvard Medical School

 3:05pm–3:35pm

Susan Whitfield-Gabrieli, PhD,

Tommy Fuss Endowed Chair in Precision Psychiatry, the Associate Director of the Center for Precision Psychiatry, Director of EPIC Lab and a member of Harvard Medical School faculty

 3:35pm–3:40pm

Brief Section Introduction

 3:40pm-4:25pm

The Use of Real-World Evidence for Prevention and Treatment in Precision Psychiatry

 3:40pm–4:25pm

 Panel Moderator:

Chris Kennedy, PhD,

Researcher, Center for Precision Psychiatry; Instructor in Psychiatry, Harvard Medical School

Katherine P. Liao, MD,

Associate Professor of Medicine and Biomedical Informatics at Harvard Medical School

Carl Marci, MD,

Director, Social Neuroscience, Psychotherapy Research Program at Massachusetts General Hospital; Chief Clinical Officer and Chief Psychiatrist and Managing Director of Mental Health and Neuroscience at OM1

Ole Andreassan, PhD,

Director, Centre of Precision Psychiatry, University of Oslo; Attending Psychiatrist, Outpatient clinic, Oslo University Hospital; Co-director KG Jebsen Centre for Neurodevelopmental disorders, University of Oslo

4:25pm–4:30pm

Closing Remarks

Time

Content

Speaker

 9:00am–9:10am

Welcome Remarks

 Jordan Smoller, MD, ScD,

Director, MGH Center for Precision Psychiatry; Professor of Psychiatry, Harvard Medical School; Director, Psychiatric and Neurodevelopmental Genetics Unit, MGH Center for Genomic Medicine

9:10am–9:50am

Conference Keynote

Steve Paul, MD,

Founder and Chair of the Board of Directors at Seaport Therapeutics and Venture Partner at Third Rock Ventures

9:50am–10:10am

 Moderated Discussion/Q&A:

Jordan Smoller, MD, ScD,

Director, MGH Center for Precision Psychiatry; Professor of Psychiatry, Harvard Medical School; Director, Psychiatric and Neurodevelopmental Genetics Unit, MGH Center for Genomic Medicine

10:10am-10:15am

Brief Section Introduction

10:15am-11:00am

What Can Precision Psychiatry Offer the DSM?

10:15am-11:00am

Anissa Abi-Dargham, MD,

Professor and Chair, Department of Psychiatry and Behavioral Health; Lourie Endowed Chair in Psychiatry at Stony Brook University; SUNY Distinguished Professor; Director, Multi-Modal Translational Imaging Lab; Associate Dean and Associate Vice President, Clinical and Translational Science; Principal Investigator, Long Island Network for Clinical and Translational Science

Roman Kotov, PhD,

Associate Professor at Stony Brook University; Hierarchical Taxonomy of Psychopathology (HiTOP) Consortium Workgroup Executive Committee

Jordan Smoller, MD, ScD,

Director, MGH Center for Precision Psychiatry; Professor of Psychiatry, Harvard Medical School; Director, Psychiatric and Neurodevelopmental Genetics Unit, MGH Center for Genomic Medicine

Panel Moderator:

Maurizio Fava, MD,

Chair, Mass General Brigham Academic Medical Centers Psychiatry Department and Executive Director, Massachusetts General Hospital (MGH) Clinical Trials Network and Institute (CTNI); Slater Family Professor of Psychiatry at Harvard Medical School

11:00am-11:10am

BREAK

11:10am-11:15am

Brief Section Introduction

11:15am–12:35pm

Perspectives on Psychedelics

11:15am-12:35am

Rachel Yehuda, PhD,

Chemers Neustein Family Professor of Trauma and Resilience, Vice Chair of Veterans Affairs in the Department of Psychiatry, and Director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai

11:35am-11:55am

Matthew Johnson, PhD,

Associate Professor of Psychiatry and Behavioral Sciences at Johns Hopkins University

11:55am-12:15pm

Michael Wheeler, PhD,

Assistant Professor, Harvard Medical School, Brigham & Women’s Hospital

12:15pm-12:35pm

Panel Moderator:

Franklin King IV, MD,

Instructor, Massachusetts General Hospital/Harvard Medical School Research Associate, Department of Psychology

12:35pm–1:35pm

BREAK FOR LUNCH

1:35pm-1:40pm

Brief Section Introduction

1:40pm-2:20pm

From Synapses to Circuits: Toward Precision Neuropsychiatry

1:40pm-2:00pm

Steven A. Kushner, MD, PhD,

Professor of Psychiatry at the Vagelos College of Physicians and Surgeons at Columbia University; Co-Director of the Stavros Niarchos Foundation Center for Precision Psychiatry and Mental Health; Principal Investigator at the New York State Psychiatric Institute

2:00pm-2:20pm

Joseph J. Taylor, MD, PhD,

Medical Director of TMS, BWH Center for Brain Circuit Therapeutics; Director, MGB Noninvasive Neuromodulation Clinical Trials; Associate Program Director and Research Track Co-Director, BWH/HMS Psychiatry Residency Program; Director, BWH Interventional Psychiatry Research Program; Jonathan F. Borus, MD, Endowed Chair in Psychiatry;

Assistant Professor of Psychiatry, Harvard Medical School

2:20pm-2:25pm

Brief Section Introduction

2:25pm-3:05pm

Toward Precision Treatment of Mood Disorders

2:25pm-2:45pm

Andrea Cipriani, MD, PhD,

NIHR Research Professor; Director, Global Alliance for Living Evidence on Depression, Anxiety and Psychosis; and Director, NIHR Oxford Health Clinical Research Facility

2:45pm-3:05pm

Nicholas C. Jacobson, PhD,

Associate Professor in Biomedical Data Science, Psychiatry, and Computer Science; Center for Technology and Behavioral Health

Geisel School of Medicine at Dartmouth College

3:05pm-3:10pm

Brief Section Introduction

3:10pm–3:55pm

AI and Mental Health: A Challenging Future

3:10pm-3:55pm

Panel Moderator:

Taylor Burke, PhD, Associate Professor of Psychology in the Department of Psychiatry at MGH

Rebecca Brendel, MD, JD,

Director, HMS Center for Bioethics, Associate Professor of Psychiatry, Francis Glessner Lee Associate Professor of Global Health and Social Medicine in the Field of Legal Medicine

Isaac R. Galatzer-Levy, PhD,

Adjunct Assistant Professor, Department of Psychiatry at NYU Grossman School of Medicine

Kate H. Bentley, PhD,

Senior Clinical Safety Officer at Spring Health

3:55pm-4:05pm

BREAK

4:05pm-4:10pm

Brief Section Introduction

4:10pm-4:55pm

From Polygenic Risk to Practice: Lessons from Clinical Implementation

4:10pm-4:55pm

Panel Moderator:

Rebecca Fortgang, PhD, Clinical Psychologist and Assistant Professor at Harvard Medical School/Massachusetts General Hospital

Jason Vassy, MD, MPH, MS,

Director, Genomes2Veterans; Clinician-Investigator, VA Boston Health Care System; Associate Professor of Medicine, Harvard Medical School

Jehannine “J9” Austin, PhD, MSc (Genetic Counselling) CCGC/CGC, FCAHS; Head

and Professor, Department of Medical Genetics; Professor, UBC Department of

Psychiatry; Research Scientist, BC Mental Health and Substance Use Services Research

Institute, Vancouver; Centre Investigator, Brain Research Centre, University of British

Columbia, Vancouver; Team Leader, Translational Genetics Research Collaborative,

BC Children’s Hospital Research Institute

Pradeep Natarajan, MD, MMSc,

Director of Preventive Cardiology, Massachusetts General Hospital; Paul & Phyllis Fireman Endowed Chair in Vascular Medicine, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School

4:55pm-5:00pm

Brief Section Introduction

5:00pm-5:30pm

Emerging Innovators in Precision Psychiatry

5:00pm-5:05pm

TBD – To be determined/awarded 2027

5:05pm-5:10pm

Highlighted by Susan Whitfield-Gabrieli, PhD,

Tommy Fuss Endowed Chair in Precision Psychiatry, the Associate Director of the Center for Precision Psychiatry, Director of EPIC Lab and a member of Harvard Medical School faculty

5:10pm-5:15pm

TBD – To be determined/awarded 2027

5:15pm-5:20pm

Highlighted by Susan Whitfield-Gabrieli, PhD,

Tommy Fuss Endowed Chair in Precision Psychiatry, the Associate Director of the Center for Precision Psychiatry, Director of EPIC Lab and a member of Harvard Medical School faculty

5:20pm-5:30pm

Closing Remarks and Thank You